Disruptions in this microbial ecosystem, known as dysbiosis, have been linked to a range of diseases, including obesity, diabetes, cardiovascular disease, and mental health disorders like depression and anxiety, highlighting its critical role in systemic health (Zhao et al., 2023
The A-NPs@(SHK+Ce6) nanosystem incorporates CaCO3 nanoparticles to buffer excess H+ ions and alleviate suppressive conditions, while the loaded SHK peptide inhibits lactate production and synergizes with photodynamic therapy to repolarize TAMs toward the M1 phenotype (53)
Therapy-induced metabolic reprogramming also plays a central role in the induction of cellular dormancy, epithelialmesenchymal transition (EMT), and the emergence of drug-tolerant persister cell populations [28]
Resistance mechanisms to immune checkpoint inhibitors: updated insights
It modulates the expression of genes involved in immune signaling, including those related to the IL-6 pathway that is consistently dysregulated in SLE
Effectively synthesized functional Si-doped carbon Dots with the applications in tyrosinase detection and lysosomal imaging